If you love pizza and burgers, why not combine them into one delicious, easy-to-make dish? Slow Cooker Pepperoni Pizza Burgers bring the best of both worlds together, offering juicy, flavorful burger patties smothered in rich pizza sauce, topped with melted mozzarella cheese, and infused with classic Italian seasonings.

This recipe is perfect for busy weeknights, game nights, or when you want to serve something unique without spending hours in the kitchen. By using a slow cooker, you allow the flavors to deepen over time, creating a tender, cheesy, and mouthwatering meal that the whole family will love.

Unlike traditional burgers, which require constant monitoring on the stovetop or grill, this recipe lets your slow cooker do all the work. With just a few minutes of prep and a handful of ingredients, you’ll have a meal that tastes like it came straight from your favorite pizzeria. Plus, using lean ground beef and turkey pepperoni makes this dish a slightly healthier alternative to greasy fast food burgers.

Want to learn more about how slow cookers work and why they make meals so flavorful? Check out this in-depth guide on slow cooking. Now, let’s dive into why you’ll love this dish!

Why You’ll Love This Recipe

There are plenty of reasons to make these Slow Cooker Pepperoni Pizza Burgers part of your meal rotation. Whether you’re a fan of classic burgers, cheesy pizza, or just looking for an easy and satisfying dinner, this recipe checks all the boxes.

1. Easy and Convenient

With minimal prep, this dish is slow cooker-friendly, meaning you can set it and forget it. No need to stand over a grill or stove!
Perfect for busy families, meal prepping, or days when you don’t want to spend too much time cooking.

2. A Unique Twist on a Classic

These burgers combine the savory goodness of a burger with the bold flavors of pepperoni pizza.
Instead of a traditional burger sauce, the patties are covered in rich pizza sauce and topped with melted mozzarella and Parmesan cheese.
Love experimenting with food? Check out these pizza-inspired recipes for more creative ideas!

3. Perfect for Any Occasion

Great for family dinners, game nights, or even casual gatherings with friends.
Serve with fries, a fresh salad, or garlic bread for a complete meal.
Kid-friendly and adult-approved—everyone will love this dish!

If you’re a fan of cheesy comfort foods, you’ll love these burgers. Get inspired by these delicious cheesy recipes that bring out the best in every bite! Now, let’s take a closer look at the ingredients that make this dish so flavorful.

Ingredients Breakdown

To make the best Slow Cooker Pepperoni Pizza Burgers, you need a combination of high-quality ingredients that bring out the rich, cheesy, and savory flavors. Below is a breakdown of each component and why it’s essential for this dish.

For the Burgers

Ground Beef (1 ½ lbs) – Using 80/20 ground beef ensures your burgers are juicy without being overly greasy. If you prefer a leaner option, you can substitute with ground turkey or chicken. Learn more about the history of hamburgers and their evolution over time.
Italian Seasoning (1 tsp) – A blend of dried herbs like oregano, basil, thyme, and rosemary that enhances the pizza-inspired flavors.
Garlic Powder (½ tsp) & Onion Powder (½ tsp) – These add depth and a rich umami flavor to the patties without overpowering them.
Salt (½ tsp) & Black Pepper (¼ tsp) – Essential seasonings to balance the taste and bring out the flavors of the meat.

For the Sauce

Pizza Sauce (1 can, 15 oz) – The base of the dish, this sauce gives the burgers their signature pizza flavor. Opt for a high-quality store-bought sauce or make your own for a fresher taste. Looking for more ideas? Browse these homemade pizza sauce recipes.
Diced Turkey Pepperoni (½ cup) – A slightly healthier alternative to traditional pepperoni, adding a smoky and slightly spicy kick. Want to know what makes pepperoni unique? Check out this guide on pepperoni.
Dried Oregano (1 tsp) – Enhances the Italian flavors and complements the cheese and tomato sauce.
Crushed Red Pepper Flakes (½ tsp, optional) – If you enjoy a bit of heat, this ingredient adds a slight kick without overpowering the dish.

For Assembly

Hamburger Buns (4) – Brioche buns add a touch of sweetness, while sesame seed buns give a classic burger feel. For a low-carb option, serve the burgers in lettuce wraps.
Shredded Mozzarella Cheese (1 cup) – The key to a gooey, melty topping that makes these burgers taste like a slice of pizza. Learn more about mozzarella cheese and why it’s perfect for melting.
Grated Parmesan Cheese (¼ cup) – Adds a nutty, salty bite that enhances the overall flavor profile.

Choosing the right ingredients ensures that your Pizza Burgers are flavorful, cheesy, and perfectly seasoned. Now that you have everything ready, let’s dive into the step-by-step instructions!

Step-by-Step Instructions

Now that you have all the ingredients ready, it’s time to put everything together. Follow these simple steps to make the perfect Slow Cooker Pepperoni Pizza Burgers.

Step 1: Preparing the Burger Patties

In a large mixing bowl, combine the ground beef, Italian seasoning, garlic powder, onion powder, salt, and black pepper.
Gently mix the ingredients using your hands or a spatula until just combined. Avoid overmixing, as this can make the burgers dense.
Divide the mixture into four equal portions and shape them into patties, ensuring they are slightly larger than your burger buns. The patties will shrink slightly as they cook.

Tip: If you love experimenting with burger flavors, check out these slow cooker burger ideas for more inspiration!

Step 2: Browning the Patties

Heat a skillet or grill pan over medium-high heat.
Lightly brown each patty for about 2-3 minutes per side. The goal is not to cook them through but to develop a flavorful crust.
Once browned, place the patties in the bottom of your slow cooker in a single layer.

Why is browning important? This step locks in juices and adds a rich, caramelized flavor. If you’re curious about the science behind browning meat, read more about the Maillard reaction.

Step 3: Preparing the Sauce

In a small bowl, mix the pizza sauce, diced turkey pepperoni, dried oregano, and crushed red pepper flakes (if using).
Stir until well combined.
Pour the sauce evenly over the burger patties in the slow cooker, ensuring each patty is fully coated.

Step 4: Slow Cooking the Burgers

Cover the slow cooker with the lid and cook on low for 4-5 hours or high for 2-3 hours.
Avoid opening the lid frequently, as this can release heat and extend cooking time.

Tip: The longer cooking time allows the flavors to meld together, making the burgers even more delicious. For more tips on slow cooking, check out these slow cooker meal prep ideas.

Step 5: Melting the Cheese

About 10 minutes before serving, sprinkle the shredded mozzarella and grated Parmesan cheese evenly over the patties.
Cover the slow cooker again and let the cheese melt until it’s gooey and bubbly.

Step 6: Assembling and Serving

Toast the hamburger buns if desired. This adds a crispy texture and helps prevent the buns from becoming soggy.
Using a spatula, carefully place each cheesy burger patty onto a bun.
Spoon extra pizza sauce from the slow cooker onto the burgers for added flavor.
Serve immediately with your favorite sides!

Now that your Slow Cooker Pepperoni Pizza Burgers are ready, let’s explore some expert tips to make them even better.

Tips for the Best Slow Cooker Pizza Burgers

Making the perfect Slow Cooker Pepperoni Pizza Burgers is easy, but a few expert tips can take them to the next level. Whether you want juicier patties, richer flavor, or the perfect bun-to-burger ratio, these tips will ensure your meal is a hit.

1. Use the Right Ground Beef

An 80/20 blend (80% lean meat, 20% fat) is ideal for juicy burgers without excessive grease.
If you prefer a leaner option, try ground turkey or chicken, but add a tablespoon of olive oil to keep the patties moist.

2. Don’t Skip Browning the Patties

Searing the patties before slow cooking locks in juices and enhances the umami flavor.
If you’re short on time, you can skip this step, but your burgers might be slightly softer in texture.

3. Prevent the Burgers from Drying Out

Don’t overcook! Cooking on low for 4-5 hours is best for juicy patties. If cooking on high, don’t exceed 3 hours.
Placing a layer of parchment paper at the bottom of the slow cooker can help prevent sticking.

4. Make the Sauce Even Richer

Add sautéed mushrooms, diced bell peppers, or extra garlic for a deeper flavor.
Stir in a tablespoon of tomato paste to make the sauce thicker and more intense.
Want more creative sauce ideas? Check out these homemade pizza sauce recipes.

5. Keep the Buns from Getting Soggy

Toast the buns before assembling the burgers to create a crispy barrier.
Serve the burgers open-faced with the sauce on top instead of the bottom bun.
If making ahead, store the buns separately and assemble just before serving.

Want to explore more burger-making techniques? Here’s a guide on the origin of hamburgers and how they’ve evolved.

With these expert tips, your Slow Cooker Pepperoni Pizza Burgers will turn out perfectly every time. Now, let’s explore some delicious variations and substitutions!

Variations and Substitutions

One of the best things about Slow Cooker Pepperoni Pizza Burgers is their versatility. Whether you’re looking for a healthier alternative, a vegetarian option, or just a fun twist on the original recipe, there are plenty of ways to customize this dish to suit your taste.

1. Swap the Protein

Ground Turkey or Chicken – A leaner alternative to beef that still delivers great flavor. Add a bit of olive oil to prevent dryness.
Plant-Based Burgers – Use your favorite veggie or meatless burger patties to create a vegetarian version. Look for plant-based ground beef substitutes that mimic the texture of real meat.
Sausage Patties – For a more pizza-like taste, try using Italian sausage patties instead of ground beef.

2. Change Up the Cheese

Provolone or Cheddar – If you’re not a fan of mozzarella, these cheeses provide a rich and creamy alternative.
Pepper Jack – Adds a spicy kick for those who love heat.
Dairy-Free Cheese – Perfect for those who are lactose intolerant or following a vegan diet.

3. Make It Gluten-Free or Low-Carb

Use Lettuce Wraps – Swap out the bun for crisp lettuce leaves for a low-carb, keto-friendly meal.
Gluten-Free Buns – Available at most grocery stores, these are a great option for those with gluten sensitivities.

4. Try Different Toppings

Sautéed Mushrooms & Onions – Adds a deep, earthy flavor that complements the pizza sauce.
Banana Peppers or Jalapeños – Perfect for a spicy twist.
Fresh Basil or Arugula – A great way to add freshness to balance out the richness of the cheese.

For more inspiration, check out these pizza-themed dishes and get creative with your own variations!

Now that we’ve covered different ways to customize the recipe, let’s explore the best sides to serve with these delicious burgers.

Side Dishes That Pair Well

A great burger deserves an equally delicious side dish! These Slow Cooker Pepperoni Pizza Burgers pair well with a variety of sides, whether you’re craving something crispy, refreshing, or indulgent. Here are some of the best options to complete your meal.

1. Garlic Parmesan Fries

A flavorful twist on classic fries, garlic Parmesan fries are crispy, cheesy, and packed with flavor.
Sprinkle with freshly grated Parmesan cheese and chopped parsley for extra taste.
For a healthier option, try baking or air-frying the fries instead of deep-frying.

2. Caesar Salad

A light and fresh side that balances the richness of the burgers.
Toss crisp romaine lettuce with Caesar dressing, croutons, and grated Parmesan cheese.
Add cherry tomatoes or bacon bits for extra crunch.

3. Zucchini Fries (Low-Carb Option)

A great alternative to regular fries, these crispy baked zucchini fries are both delicious and keto-friendly.
Coat zucchini strips in Parmesan cheese and almond flour for a crunchy texture.

4. Sweet Potato Fries

If you love a sweet-savory contrast, sweet potato fries are a perfect match for these pizza burgers.
Bake them with a sprinkle of paprika, garlic powder, and sea salt for extra flavor.

5. Coleslaw

A cool, crunchy coleslaw adds a refreshing contrast to the warm, cheesy burgers.
Try a classic mayo-based slaw or a light vinegar-based slaw for a tangy twist.

Want more easy dinner ideas? Check out these family dinner recipes for more inspiration!

Now that we’ve covered the best side dishes, let’s talk about how to store and reheat your leftovers.

Storage and Reheating Tips

If you have leftover Slow Cooker Pepperoni Pizza Burgers, don’t worry—they store and reheat beautifully! Follow these simple steps to keep your burgers fresh and delicious.

1. Storing Leftovers

Refrigerator: Store the burger patties and sauce in an airtight container for up to 3 days. Keep the buns separate to prevent them from getting soggy.
Freezer: If you want to freeze the patties, let them cool completely, then wrap each one individually in plastic wrap and store them in a freezer-safe container. They’ll last up to 3 months.

2. Best Ways to Reheat

Stovetop: Heat a skillet over medium heat and warm the patty for 3-5 minutes per side. Add extra sauce to keep it moist.
Oven: Preheat the oven to 350°F (175°C) and bake the patties for 10-15 minutes until heated through.
Microwave: Place the patty on a microwave-safe plate, cover with a damp paper towel, and heat in 30-second intervals until warm.
Slow Cooker: If reheating multiple patties, place them back in the slow cooker on low for about 30-45 minutes.

3. Freezing for Meal Prep

Assemble the uncooked patties, stack them with parchment paper in between, and freeze. When ready to cook, thaw overnight in the fridge before following the original cooking instructions.
You can also freeze cooked patties and reheat them directly in the slow cooker with extra sauce.

For more slow cooker meal prep ideas, check out these freezer-friendly recipes.

Now that you know how to store and reheat your burgers, let’s go over some frequently asked questions.

Frequently Asked Questions (FAQs)

Still have questions about making Slow Cooker Pepperoni Pizza Burgers? Here are some common questions and answers to help you perfect this recipe.

1. Can I use regular pepperoni instead of turkey pepperoni?

Yes! Regular pepperoni works just as well, but it tends to be higher in fat. If using regular pepperoni, consider draining excess grease after cooking. Want to learn more about what pepperoni is made of? Check out this guide on pepperoni.

2. How do I make this recipe spicier or milder?

To make it spicier, add extra crushed red pepper flakes, hot sauce, or use spicy Italian sausage instead of ground beef.
To make it milder, skip the red pepper flakes and opt for a mild pizza sauce.

3. Can I cook these burgers on the stovetop instead of a slow cooker?

Yes! If you prefer a faster method, cook the patties in a skillet over medium heat for 5-7 minutes per side, then top with sauce and cheese. Cover and simmer for a few minutes until the cheese melts.

4. What are the best buns to use for this recipe?

Brioche buns – Soft and slightly sweet, perfect for balancing the savory flavors.
Sesame seed buns – A classic choice with added texture.
Pretzel buns – A sturdy option that holds up well to the sauce.
Gluten-free buns – Great for those with dietary restrictions.

5. How do I make this dish keto-friendly?

To make this recipe low-carb and keto-friendly:

Use lettuce wraps instead of buns.
Swap pizza sauce for a low-sugar marinara sauce.
Stick to full-fat cheese and avoid processed toppings.

Slow Cooker Pepperoni Pizza Burgers

Author: Christopher

Print Recipe

Description

These Slow Cooker Pepperoni Pizza Burgers combine the best of two comfort foods—juicy burgers and cheesy pepperoni pizza! Made with seasoned ground beef patties, rich pizza sauce, melted mozzarella and Parmesan cheese, and flavorful turkey pepperoni, this dish is an easy and delicious way to switch up your burger night.

Using a slow cooker allows the flavors to blend perfectly while keeping the patties tender and juicy. Whether you’re hosting a game night, planning a family dinner, or just craving something cheesy and satisfying, these pizza burgers are sure to be a hit!

Ingredients

Scale

For the burgers:

1 ½ lbs ground beef
1 teaspoon Italian seasoning
½ teaspoon garlic powder
½ teaspoon onion powder
½ teaspoon salt
¼ teaspoon black pepper

For the sauce:

1 can (15 oz) pizza sauce
½ cup diced turkey pepperoni
1 teaspoon dried oregano
½ teaspoon crushed red pepper flakes (optional)

For assembly:

4 hamburger buns
1 cup shredded mozzarella cheese
¼ cup grated Parmesan cheese

Instructions

In a large bowl, mix the ground beef with Italian seasoning, garlic powder, onion powder, salt, and black pepper. Form into 4 burger patties.

Heat a skillet over medium-high heat and lightly brown the patties for 2-3 minutes on each side (they don’t need to be fully cooked).

Place the patties in the slow cooker.

In a small bowl, mix the pizza sauce, diced turkey pepperoni, oregano, and crushed red pepper flakes. Pour over the patties in the slow cooker.

Cover and cook on low for 4-5 hours or on high for 2-3 hours.

About 10 minutes before serving, sprinkle mozzarella and Parmesan cheese over the burgers. Cover and let the cheese melt.

Toast the hamburger buns if desired. Serve the burgers on buns with extra sauce from the slow cooker.

Notes

Choosing the Right Beef: For the juiciest burgers, use 80/20 ground beef. Leaner meats (like turkey or chicken) work too but may require a splash of olive oil to prevent dryness.
Don’t Skip Browning: Searing the patties before slow cooking adds extra flavor and prevents them from falling apart.
Spice Level: If you love a little heat, add extra crushed red pepper flakes or use spicy pepperoni. To keep it mild, stick to regular pizza sauce and omit the red pepper.
Cheese Choices: While mozzarella and Parmesan create the perfect pizza-like flavor, feel free to experiment with provolone, cheddar, or pepper jack for variety.
Serving Suggestions: These burgers pair well with garlic Parmesan fries, Caesar salad, or sweet potato fries for a complete meal.
Storage Tips: Leftovers can be stored in an airtight container in the refrigerator for up to 3 days or frozen for up to 3 months. Reheat in a skillet, oven, or microwave for the best results.